The Catholic Physicians' Guild of Chicago is a local chapter of the 6000 member strong National Federation of Catholic Physicians' Guilds. Members are dedicated to the "Service of God and man". This goal is accomplished through prayer, serious examination of moral issues and camaraderie among guild members. Quarterly plenary dinner meetings feature distinguished speakers that address important moral issues.

The Catholic Physicians' Guild of Chicago also sponsors the Catholic Medical Students Association and publishes a newsletter to instruct medical students and residents in the area of Catholic Medical Ethics. The guild offers Catholic medical students in the Chicago area many opportunities to mature as student-physicians from a uniquely Catholic perspective in the art of medicine. The Guilds' mentor program allows students to become well acquainted with a physician in their area of interest. Monthly journal club meetings also enable practicing Catholic physicians and medical students an opportunity to interact and discuss morally relevant issues.